Title

Michael Davis

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Title/Position
Professor, Associate Chair for Graduate Studies, Director, Children's Heart Research and Outcomes (HeRO) Center
Areas of Research

Areas of Research

Biomaterials & Regenerative Technologies, Cardiovascular Engineering
Contact

Contact

HSRB II N142Emory
medavis@emory.edu
404.727.9858
Davis Lab
Education

Education

  • PhD Pharmarcology, 2003-Emory University
  • BA Biology, 1998-Rutgers University
Affiliated Centers & Institutes

Affiliated Centers & Institutes

Research Interests

Research Interests

Prof. Davis’ research focuses on the design and development of biomolecular and biomaterial systems for targeted drug delivery and regenerative medicine. His work investigates molecular interactions, controlled release mechanisms, and tissue engineering scaffolds to improve therapeutic outcomes. This research integrates principles from chemistry, biology, and engineering to create innovative solutions for complex biomedical problems, with active participation from graduate and undergraduate researchers.

Our laboratory focuses on various aspects of cardiac regeneration and preservation using molecular-based and biomaterials-based approaches to restoring function after cardiac injury. By using computational systems modeling and novel stem cell-based engineering, we can repair the adult and pediatric heart.

Teaching Interests

Teaching Interests

Prof. Davis’ teaching interests center on foundational and advanced courses in biomedical engineering, including biomolecular engineering, drug delivery, and tissue engineering. His instruction emphasizes integrating engineering principles with biological systems to solve medical challenges, fostering student engagement at both undergraduate and graduate levels. Professor Davis actively involves students in research projects, promoting hands-on learning and interdisciplinary collaboration within the biomedical engineering curriculum.
Publications

Publications

Dr. Davis's research
Kaushal S, Hare JM, Mahle WT, Khan A, Ohye RG, Slesnick TC, Chai PJ, Shashidharan S, Robinson JD, Jone PN, Doman T, Si MS, Lu JC, Bacallao K, Nettina AE, Lamazares R, Saltzman RG, Simpson LM, Li R, Bettencourt JE, Mansoor K, Davis BR, Deatrick KB, Yang J, Mishra R, Everett AD, Lai D, Davis ME. Phase I Randomized Study of Cardiac Stem Cells in Patients With Hypoplastic Left Heart Syndrome: The CHILD Trial. JACC Heart Fail. 2026 Jan;14(1):102723. doi: 10.1016/j.jchf.2025.102723. Epub 2025 Nov 19. PMID: 41258851.
Brazhkina O, Park JH, Brown M, Walcott JC, Han J, Turchetti A, Roychowdhury S, Prasad RS, Kim MJ, Itzhaki I, De Jesus Morales KJ, Hollister SJ, Davis ME. In vivo assessment of iPSC-cardiomyocyte loaded auxetic cardiac patches following chronic myocardial infarction. Biomaterials. 2025 Dec;323:123418. doi: 10.1016/j.biomaterials.2025.123418. Epub 2025 May 20. PMID: 40408975.
Bheri S, Hoffman JR, Park HJ, Roychowdhury S, Takaesu F, Moore SG, Gaul DA, Davis ME. Composition of cardiac-derived extracellular vesicles changes with vesicle origin and determines uptake. Front Cardiovasc Med. 2025 Sep 15;12:1565104. doi: 10.3389/fcvm.2025.1565104. PMID: 41030476; PMCID: PMC12477219.
Hunter JD, Mesfin JM, Ahmed T, Chen A, Reimold K, Hancko A, Braden RL, Davis ME, Christman KL. Myocardial Matrix Hydrogels Mitigate Negative Remodeling and Improve Function in Right Heart Failure Model. JACC Basic Transl Sci. 2024 Mar 6;9(3):322-338. doi: 10.1016/j.jacbts.2024.01.006. PMID: 38559631; PMCID: PMC10978413.
Hoffman JR, Park HJ, Bheri S, Platt MO, Hare JM, Kaushal S, Bettencourt JL, Lai D, Slesnick TC, Mahle WT, Davis ME. Statistical modeling of extracellular vesicle cargo to predict clinical trial outcomes for hypoplastic left heart syndrome. iScience. 2023 Sep 21;26(10):107980. doi: 10.1016/j.isci.2023.107980. PMID: 37868626; PMCID: PMC10589850.
Media

Media

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