Title

Francisco E Robles

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Photo of Francisco Robles
Title/Position
Associate Professor
Areas of Research

Areas of Research

Biomedical Imaging & Instrumentation , Cancer Technologies , Biomaterials & Regenerative Technologies
Contact

Contact

U.A. Whitaker, office 3110Georgia Tech
robles@gatech.edu
404.385.2989
Optical Imaging and Spectroscopy Lab
Education

Education

  • Ph.D. in Medical Physics, 2011 - Duke University
  • B.S. in Physics, 2007 - North Caroline State University
  • B.S. in Nuclear Engineering, 2007 - North Caroline State University
Academic Appointments

Academic Appointments

Adjuct in ECE and ME
Research Interests

Research Interests

We focus on developing and applying label-free linear and nonlinear optical methods, along with advanced signal processing methods, to gain access to novel forms of functional and molecular contrast for a variety of biomedical applications. 

Teaching Interests

Teaching Interests

My teaching interests are in medical imaging, image/signal processing, optics and microscopy, and fundamental engineering. I have taught both graduate and undergraduate courses.
Publications

Publications

https://doi.org/10.1364/OPTICA.574860
C. Serafini†, A. Davarzani†, D. Cappabianca, Z. Li, D. Baez Collazos, D. Mamaghani, L. Mao, K. Saha, L. Karumbaiah, and F.E. Robles*. “Longitudinal and continuous label-free monitoring of glioblastoma patient-derived tumor spheroid treatment response using quantitative oblique back illumination microscopy,” Optica , 13 (2), 211-226, 2026
https://doi.org/10.1016/j.labinv.2025.104102
V. Gorti, A. Rajaraman Subramanian, J. Nsonwu-Farley, R. Tran, E.K. Williams, O. Torres, W. Aumann, A. Aljudi, F. E. Robles*. “Rapid, point-of-care bone marrow aspirate adequacy assessment via deep ultraviolet microscopy,” Laboratory Investigation, 105 (5), 104102, 2025
https://doi.org/10.1364/BOE.544778
V. Gorti, K. McCubbins, D. Houston, A.D. Silva Trenkle, A. Holberton, C.E. Serafini, L. Wood, G. Kwong, and F.E. Robles*, “Quantifying UV-induced photo-damage for longitudinal live-cell imaging applications of deep-UV microscopy,” Biomedical Optics Express, 16 (1), 2025
https://doi.org/10.1364/OPTICA.502859
T.M. Abraham, P. Casteleiro Costa, C. Filan, Z. Guang, Z. Zhang, S. Neill, J.J. Olson, R. Levenson, F.E. Robles*, “Label- and slide-free tissue histology using 3D epi-mode quantitative phase imaging and virtual hematoxylin and eosin staining,” Optica 10 (12), 2023
https://www.osapublishing.org/boe/fulltext.cfm?uri=boe-12-3-1621&id=448594
P. Casteleiro Costa, Z. Guang, P. Ledwig, Z. Zhang, S. Neill, J. J. Olson, F.E. Robles*, “Towards in-vivo label-free detection of brain tumor margins with epi-illumination tomographic quantitative phase imaging,” Biomedical Optics Express 12 (3), 1621-1634, 2021
https://www.osapublishing.org/optica/fulltext.cfm?uri=optica-8-1-6&id=445594
P. Ledwig, F.E. Robles*, “Quantitative 3D Refractive Index Tomography of Opaque Samples in Epi-mode,” Optica 8 (1), 2021
https://www.pnas.org/content/early/2020/06/18/2001404117
A. Ojaghi, G. Carrazana, C. Caruso, A. Abbas, D.R. Myers, W.A. Lam, F.E. Robles*, “Label-free Hematology Analysis Using Deep-Ultraviolet Microscopy,” PNAS 117 (26), 2020
https://www.osapublishing.org/boe/abstract.cfm?uri=boe-10-7-3605
P. Ledwig, F.E. Robles*, “Epi-mode tomographic quantitative phase imaging in thick scattering samples,” Biomedical Optics Express 10 (7), 3605-3621, 2019