Title

Joscelyn C Mejías

(she/her)
Headshot Placeholder
headshot of assistant professor Joscelyn Mejias
Title/Position
Assistant Professor
Areas of Research
Contact

Contact

UAW 3121Georgia Tech
(404) 385-0124
Education

Education

  • B.A. Asian Studies, Rice University
  • B.S. Bioengineering, Rice University
  • M.S. Biomedical Engineering, Emory University and The Georgia Institute of Technology
  • Ph.D Biomedical Engineering, Emory University and The Georgia Institute of Technology
Affiliated Centers & Institutes

Affiliated Centers & Institutes

Research Interests

Research Interests

Professor Mejias' research focuses on the development of biomaterial systems for immune mediated tissue regeneration and development of in vitro models for fibrosis. We are particularly interested in understanding and developing material systems that account for endogenous immune changes caused by biologic variability such as age and sex. We are also interested in using our biomaterials expertise to develop more physiologically relevant in vitro models to recapitulate human-specific fibrotic diseases such as uterine fibroids.   

Teaching Interests

Teaching Interests

Professor Mejias’ teaching interests are in biomaterials, immune tissue regeneration, and Women's Health. Her approach integrates laboratory and theoretical components, fostering student engagement and critical thinking. Dr. Mejias is committed to mentoring students through interdisciplinary training that bridges engineering principles and biological systems, supporting their development as proficient researchers and practitioners in biomedical engineering.
Publications

Publications

Mejías JC, Nelson MR, Liseth O, Roy K. A 96-well format microvascularized human lung-on-a-chip platform for microphysiological modeling of fibrotic diseases. Lab Chip. 2020 Sep 29;20(19):3601-3611. doi: 10.1039/d0lc00644k. PubMed PMID: 32990704.
Nelson MR, Ghoshal D, Mejías JC, Rubio DF, Keith E, Roy K. A multi-niche microvascularized human bone marrow (hBM) on-a-chip elucidates key roles of the endosteal niche in hBM physiology. Biomaterials. 2021 Mar;270:120683. doi: 10.1016/j.biomaterials.2021.120683. Epub 2021 Jan 25. PubMed PMID: 33556648.
Han J, Cherry C, Mejías JC, Krishnan K, Ruta A, Maestas DR Jr, Peña AN, Nguyen HH, Nagaraj S, Yang B, Gray-Gaillard EF, Rutkowski N, Browne M, Tam AJ, Fertig EJ, Housseau F, Ganguly S, Moore EM, Pardoll DM, Elisseeff JH. Age-associated Senescent - T Cell Signaling Promotes Type 3 Immunity that Inhibits the Biomaterial Regenerative Response. Adv Mater. 2024 Oct;36(43):e2310476. doi: 10.1002/adma.202310476. Epub 2023 Dec 28. PubMed PMID: 38087458; PubMed Central PMCID: PMC12522171.
Sommerfeld SD, Zhou X, Mejías JC, Oh BC, Maestas DR Jr, Furtmüller GJ, Laffont PA, Elisseeff JH, Brandacher G. Biomaterials-based immunomodulation enhances survival of murine vascularized composite allografts. Biomater Sci. 2023 May 30;11(11):4022-4031. doi: 10.1039/d2bm01845d. PubMed PMID: 37129566; PubMed Central PMCID: PMC12503134.
Mejías JC, Forrest OA, Margaroli C, Frey Rubio DA, Viera L, Li J, Xu X, Gaggar A, Tirouvanziam R, Roy K. Neutrophil-targeted, protease-activated pulmonary drug delivery blocks airway and systemic inflammation. JCI Insight. 2019 Dec 5;4(23). doi: 10.1172/jci.insight.131468. PubMed PMID: 31661469; PubMed Central PMCID: PMC6962027.