At the Center for Immunoengineering engineers, chemists, physicists, computational scientists and immunologists come together to collaboratively understand how the immune system works and find breakthrough solutions to improve the lives of patients suffering from cancer, infectious diseases (e.g. HIV, tuberculosis, hepatitis, polio etc.), autoimmune and inflammatory disorders (e.g. diabetes, lupus, multiple sclerosis, arthritis, fibrosis, asthma etc.) as well as those undergoing regenerative therapies (e.g. organ transplantation, spinal cord injury, bone and cartilage repair etc.).
The Nanomedicine Center for Nucleoprotein Machines is supported by the US National Institutes of Health Common Fund. It is one of the four multi-institutional Nanomedicine Development Centers.
There are an estimated 10,000 human single-gene disorders, which impose a significant burden on human health worldwide. The 5-year goals of this NDC are to develop a clinically applicable gene correction technology to treat single-gene disorders, and to demonstrate the efficacy of this approach in treating sickle cell disease (SCD) using a mouse model.
The Neural Engineering Center develops cutting-edge science and technology for measuring, understanding, modifying, and stimulating neural activity. There is a critical need for novel collaborative integration between researchers developing interfacing technologies and those advancing our scientific understanding of brain and nervous system function. Applications of these technologies span advancing understanding of neural function to translational methods that improve clinical outcomes.
This Georgia Institute of Technology research center will develop processes and techniques for ensuring the consistent, low-cost, large-scale manufacture of high-quality living cells used in cell-based therapies. The therapies will be used for a variety of disorders such as cancer, lung fibrosis, autism, neuro-degenerative diseases, autoimmune disorders and spinal-cord injury – as well as in regenerative medicine. The work of the Center will help provide standardized production and quality testing for these living cells, which have great therapeutic potential. Standardized manufacturing techniques already exist for drug-based pharmaceuticals; the new center will help provide similar methods and standards for manufacturing therapeutic cells. Expected to be the first of its kind in the United States, the center will include a validation facility for good manufacturing practices in cell production.