Stem cell engineering, stem cell bioprocessing and biomanufacturing, regenerative biomaterials, cell and tissue engineering, stem cell delivery. Read about specific research applications and research projects on the lab website.
Our lab is interested in the development of tissue models from human stem cell sources. We make micro-scale tissue “constructs,” or structures, that simulate the function of those tissues. The structures are meant to help with both drug screening in a dish and, eventually, tissue engineering in real patients.
Specifically, we’re focused on stem cell maturation—taking a cell from an immature to a more mature state so that it acts as a better substrate for adult tissue functions. We’re also very interested in what stem cells actually produce and how we can leverage that output for regenerative therapeutic purposes.
Finally, we’ve been very active in developing scalable technologies for cell manufacturing. Right now, stem cell products are commonly produced on a very small scale to use in lab experiments, but we need to make them in much greater orders of magnitude for use in future human therapies. So we want to take some of the amazing fundamental biological discoveries that have been made and start to think about how they can be applied on a larger scale in a commercially viable manner.
For specific research applications and research projects, visit the lab website.