The goal of the lab is to develop selective drug delivery systems to modulate innate and adaptive immunity. Strategies to achieve these goals are derived from the rational design of polymer-based materials and self-assembled complexes. We expand upon these materials using covalent and non-covalent modification strategies. Students will gain expertise in materials synthesis and characterization. The materials developed in the lab are tested using cell culture and preclinical autoimmune and cancer models. Mechanistic studies will be used as a feedback loop to redesign the materials as needed.