Pediatric Bioengineering is the development and application of engineering concepts, methods and approaches to improve the health of children through better diagnosis, more effective treatment and prevention of pediatric diseases. Children suffer from diseases of every organ system, arising from both congenital and acquired sources of illness. The unique physiology of a growing child changes over time and the pathophysiology of many pediatric diseases are distinct from adult diseases. This necessitates the development of pediatric bioengineering to provide a unique interdisciplinary research and educational opportunity in both engineering and pediatrics. Specific research areas of pediatric bioengineering at BME include (but are not limited to) the diagnosis and treatment of: neonatal disorders; cystic fibrosis; congenital heart disease, infectious diseases, cancers and blood diseases including sickle cell disease; pediatric neurological diseases and autism; musculoskeletal diseases and obesity. The pediatric technologies currently being developed at Georgia Tech and Emory University include: pediatric medical and surgical devices, nanomedicine and molecular imaging approaches, bioinformatics, biomaterials and computational methods. Pediatric bioengineering is expected to generate a major impact to pediatric healthcare, improving the lives of children and helping train the next-generation leaders in pediatrics and bioengineering.